Innovation in Orodispersible Dosage Forms and Its Role in Emergency Treatment
DOI:
https://doi.org/10.62382/040x0275Keywords:
Orodisperible dosage forms, Superdisintegrants, Seizures, Emergency treatment, 3D printing technology, Orodipsersible films, EpilepsyAbstract
Most of the severe neurological conditions require prompt attention to avoid major damage due to various health related conditions such as seizures, hypoglycemia, cardiac arrest and unconsciousness. In such cases, if a trained medical practitioner is not available, it might lead to severe damage to the patient health condition such as neurological damage to a seizing patient. These issues have led to finding a solution for pharmaceutical manufacturers to design a convenient drug dosage form with quick action. Orodisperible dosage forms are gaining attention among manufacturer`s market due to cost-effective methods of preparation and for clinicians to address such critical situations to save Patient`s lives. The primary feature of orodispersible dosage form is the quick disintegration due to the use of the polymer known as superdisintegrants in the formulation. In this review, discuss various orodispersible drug delivery systems with their respective manufacturing methods are discussed. Also, the major features of this delivery system and mechanism of the superdisintegrants are discussed. Furthermore, dissolution and absorption pattern of the orodispersible dosage form is also explained. The highlights related to the use of the emerging technology of 3D printing in orodispersible films is also discussed. Finally, the conclusion for the application and importance of orodispersible tablets in emergency treatment i.e., epileptic seizures is provided.
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